The College Street Historic District is significant as a collection of residential buildings built between ca. 1880 and 1925 which embrace a wide variety of architectural styles and which retains a strong sense of residential unity. Styles include vernacular Victorian, Colonial Revival, Queen Anne, Tudor Revival, and California Bungalow. The district contains nineteen residences that reflect the development of the neighborhood since its beginning as a faculty residential section for Newberry College in the 1880s. The district also includes a Gothic Revival style church. Listed in the National Register November 26, 1980.